Toll-like receptor expression in C3H/HeN and C3H/HeJ mice during Salmonella enterica serovar Typhimurium infection.

نویسندگان

  • Sabine Tötemeyer
  • Neil Foster
  • Pete Kaiser
  • Duncan J Maskell
  • Clare E Bryant
چکیده

Here, we have investigated the mRNA expression of Toll-like receptor 2 (TLR-2), TLR-4, and MD-2 in spleens and livers of C3H/HeN mice (carrying wild-type TLR-4) and C3H/HeJ mice (carrying mutated TLR-4) in response to Salmonella infection. During Salmonella infections, TLR-4 is activated, leading to increased TLR-2 and decreased TLR-4 expression.

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عنوان ژورنال:
  • Infection and immunity

دوره 71 11  شماره 

صفحات  -

تاریخ انتشار 2003